In Canada, researchers have concluded that steroid use among student athletes is extremely widespread. US Department of Justice. As a result, two foods could have the same glycemic index, but produce different amounts of insulin. A disadvantage with this system is that the reference food is not well-defined, because there is no universal standard for the carbohydrate content of white bread. What is the Recommended Caloric Intake for Children?
Late in 2010 the peer-reviewed Journal of Obesity published a meta-analysis of studies testing the garcinia as a weight loss aid. Of the 23 trials they identified, 12 were methodologically sound enough to include in their analysis. The analysis revealed that some statistically significant weight loss occurred, but the magnitude of the effect is small and the clinical relevance is uncertain.